Senior Physician Assistant | Clinical Lead Longevity & Metabolic Medicine

Location: Bellmore, NY (Primary) and Manhattan, NYEmployment Type: Full-TimeStarting Salary: $140,000+ annually (commensurate with experience)Schedule: Majority of workweek based in Bellmore, Long Island, with approximately 1–2 days per week in Manhattan.

About Prefusion Health

Prefusion Health is a physician-led personalized medicine practice focused on preventive healthcare, longevity medicine, metabolic optimization, hormone health, advanced diagnostics, and performance-focused care.

Our mission is to help patients achieve optimal health through evidence-based, data-driven medicine that goes beyond traditional primary care. We combine advanced laboratory analysis, body composition assessment, metabolic testing, hormone optimization, weight management, and innovative therapeutic approaches to deliver highly individualized treatment plans.

We are seeking an experienced Physician Assistant who is passionate about the future of healthcare and interested in assuming a leadership role within a growing organization.

Position Overview

The Senior Physician Assistant will serve as both a clinical provider and a clinical leader, working directly under our Medical Supervisor to help oversee practitioners, maintain clinical excellence, and support the growth of our personalized medicine programs.

This role is ideal for a PA who enjoys clinical autonomy, advanced diagnostics, patient education, and helping build innovative healthcare systems.

Primary ResponsibilitiesClinical Care

Perform comprehensive new patient consultations and follow-up evaluations
Develop personalized treatment plans based on laboratory findings, diagnostic testing, and patient goals
Order, review, and interpret advanced laboratory testing
Manage hormone optimization and metabolic health programs
Monitor and adjust treatment protocols based on patient outcomes
Maintain accurate and compliant clinical documentation
Collaborate closely with supervising physicians and medical leadership

Leadership Responsibilities

Assist in overseeing and supporting clinical practitioners
Ensure adherence to clinical protocols and standards of care
Participate in provider onboarding, mentorship, and training
Support implementation of new clinical programs and services
Assist leadership with quality assurance initiatives
Help optimize patient experience and clinical workflows
Serve as a clinical resource for providers and staff

Desired Clinical Expertise

Strong preference will be given to candidates with experience or significant interest in:

Hormone Replacement Therapy (HRT)
Testosterone Replacement Therapy (TRT)
Women's hormone optimization
GLP-1 and weight management therapies
Peptide-based therapeutic protocols
Longevity and preventive medicine
Functional and integrative medicine principles
Comprehensive laboratory analysis and biomarker interpretation
Metabolic health optimization
Cardiovascular risk assessment

Advanced Diagnostic Experience

Experience with the following is highly desirable:

DEXA body composition scanning and interpretation
VO₂ Max testing and exercise performance assessment
Resting Metabolic Rate (RMR) testing
Metabolic and cardiovascular diagnostics
Advanced biomarker analysis

Candidates without direct experience in every area are encouraged to apply if they possess a strong foundation in clinical medicine and a demonstrated willingness to learn advanced longevity and performance medicine concepts.

QualificationsRequired

Graduate of an accredited Physician Assistant program
NCCPA Certification
Active New York State PA license
Strong clinical judgment and communication skills
Ability to work independently and collaboratively
Passion for preventive and personalized medicine

Preferred

5+ years of clinical experience
Prior leadership or supervisory experience
Experience in primary care, internal medicine, endocrinology, urgent care, preventive medicine, sports medicine, or functional medicine
Experience managing hormone therapy or weight management programs

Compensation & Benefits

Starting salary of $140,000+
Leadership-track opportunity with significant growth potential
Direct collaboration with Medical Supervisor and executive leadership
Continuing education and professional development opportunities
Opportunity to become a key leader within a rapidly growing organization
Exposure to cutting-edge diagnostics and personalized medicine programs

Work Location

This position is primarily based in our Bellmore, Long Island office. Candidates should expect approximately 70–80% of their time to be spent on Long Island and 20–30% of their time in our Manhattan office, depending on patient scheduling and operational needs.

Ideal Candidate

The ideal candidate is a motivated clinician who is excited about the future of personalized medicine and enjoys combining patient care with leadership responsibilities. This individual is intellectually curious, data-driven, comfortable interpreting complex laboratory findings, and eager to become an expert in advanced longevity, metabolic, and performance medicine.

Job Type: Part-time

Pay: From $150,000.00 per year

Benefits:

Flexible schedule

Work Location: In person

Prefusion Health

Latest Jobs

Physician Assistant